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Thus, upregulation of GPx1 was associated with poor prognosis in some but not all types of renal cell carcinoma: upregulation in kidney chromophobe cell carcinoma and renal clear cell carcinoma was an indicator of a poor prognosis, whereas in renal papillary cell carcinoma, upregulation of GPx1 was associated with better outcomes [135]

Yet, the factors that determine S distribution downstream of Cys are unclear

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, 41 , 1119-1132, doi: Funding This work was financially supported by the Program 5-100 of the Peoples Friendship University of Russia