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To find potential mediator(s) responsible for upregulation of LRO mRNAs, we screened large-scale transcriptomic data for the following stress-responsive regulators: the lysosome biogenetic HLH-30 65 , the intestinal ELT-2 66 , the aryl-hydrocarbon receptor AHR-1 67 , the PMK-1-controlled oxidative and immune regulator ATF-7 68 , the heat shock factor HSF-1 69 , the major IIS effector DAF-16 70 and the xenobiotic regulator SKN-1 71 , the latter two were reported to be activated by BA and MS 26

Pineville Lancaster, Michael N

Tumor progression and the different faces of the PERK kinase

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As a positive control for typical protein corona formation on hard nanoparticles, we incubated polystyrene nanoparticles with human plasma, isolated the corona-coated particles, and imaged them using cryo-TEM (Fig