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Nat Immunol 4:269273
63 N-acetyl cysteine is the antidote to acetaminophen toxicity and a mucolytic agent
ABCB6 is dispensable for erythropoiesis and specifies the new blood group system Langereis
Using B6 as a cofactor, Hcy can also be converted to cysteine via transsulfuration for use in glutathione synthesis [34] (Figure 1)
However, prolonged or severe stress can lead to the sustained activation of the ISR and the initiation of processes leading to cell death, due in part to downstream effectors such as ATF4 and its targets, such as DDIT3 (CHOP) (Pakos-Zebrucka et al., 2016)
doi: 10.1001/archopht.122.4.598
