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Metabolic outcomes of ABHD11 inhibition in CD8 + T cells Metabolism is markedly different between immortalized cancer cells and primary cells, and while the major effect of ABHD11 inhibition in HeLa cells was on 2-OG metabolism and 2-OGDD activity, the downstream consequences of perturbing this glutaryllipoyl pathway in primary cells may differ from immortalized cancer cells

10.1056/NEJMra2026131 [DOI] [PMC free article] [PubMed] [Google Scholar] 250.Reshi ML, Su Y-C, Hong J-R

[DOI] [PubMed] [Google Scholar] 518.Harrison D, Griendling KK, Landmesser U, Hornig B, Drexler H

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