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Description
Cascade process of excitotoxic neuronal death Excessive Ca influx disrupts Ca homeostasis, overwhelming mitochondrial buffering via the uniporter

Apparent mineralocorticoid excessUpdate

According to Herculano-Houzel, 2014)

Also HS SFN showed increased expression of CAT ( p = 0.02 ) compared to the HS control group
In a transgenic mouse model encoding the mev-1 gene, which induces oxidative stress, mitochondrial oxidative damage and inflammation of the lacrimal gland was detected

Pocai, A., Obici, S., Schwartz, G
