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In the absence of MTAP, the substrate methyl thionyl adenosine (MTA) accumulates and acts as a selective inhibitor of PRMT5 to inhibit PRMT5 methylation activity, 237 whereas MAT2A can produce the PRMT5 substrate SAM, 238 allowing PRMT5 to exert its oncogenic effect

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The interpretation of results of the blood biochemistry must be combined with total growth, meat weight, fat weight and meat quality in order to be useful for designing new diets

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