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J Clin Med

B vitamins are not fat-soluble and therefore not stored in the body in significant amounts

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Note: Compounded medications are prepared based on specific patient needs or in the event of drug shortages and are not reviewed or approved by the FDA for safety or effectiveness

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In particular, combining 2-OHNA with other NAD + biosynthesis inhibitors like FK866 effectively kills NAPRT-proficient cancer cells resistant to single-agent treatments 217
