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Lex, A., Gehlenborg, N., Strobelt, H., Vuillemot, R

Research indicates that both aerobic exercise (Huang et al., 2024) and high-intensity interval training (HIIT) (Fredrickson et al., 2021) markedly enhance liver metabolism via activation of crucial pathways including NF-B, AMPK, and Nrf2

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Furthermore, the miR-128-3p inhibitor also significantly downregulated the expression levels of the nuclear factor, NRF2, and these expression levels were restored upon treatment with SB203580 or SP600125

They are reference points for researchers designing their own evidence-based protocols