glutathione mitochondrial transport GSH Autoregulatory control of mitochondrial glutathione

Glutathione peroxidases (Gpx) 1-4 are selenoproteins that convert glutathione to glutathione disulfide while reducing peroxides (including lipid peroxides) to water (393,394)

During #BlackHistoryMonth, we'd like to take a moment to celebrate the pioneering spirit of OCSO Chief Deputy Denise Demps, the highest-ranking Black woman in our agency's history

Detoxification : It helps in the detoxification of harmful substances, including heavy metals and toxins, making it crucial for liver health

Genet Mol Res (2013) 12(3):228193

Emily Ward

Lower NAD+ means reduced sirtuin activity (SIRT1, SIRT3), which further impairs mitochondrial function and fatty acid oxidation in fat cells