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Activation of glucagon-like peptide-1 receptor in microglia exerts protective effects against sepsis-induced encephalopathy via attenuating endoplasmic reticulum stress-associated inflammation and apoptosis in a mouse model of sepsis

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A decrease in cerebral glutathione has been observed in brain tissue undergoing oxidative stress both in aging and neurodegeneration

The antitumor efficacy was validated in GB orthotopic models following both intratumoral and intravenous administration, with the median survival and number of long-term survivors increasing by 50% compared to control groups

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