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Freezing reconstituted solutions isnt typically recommended, as it can sometimes damage the peptide structure

Occasional injection site irritation or digestive changes may occur early in use
10.2741/3981 39 CuiY.JiangL.ShaoY.MeiL.TaoY

J Hematol Oncol 2(18):18, 2009
The mortality rate can be high, with those animals having less severe anemia more likely to survive