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Description
10.1039/d2fo03470k 24 FajemiroyeJ

Pathways of glutamine and glutamate metabolism

While these protocols are primarily designed for adult populations, paediatric applications necessitate additional refinements

The underlying mechanisms involve alterations in intestinal permeability, abnormal microbial metabolites, the actions of neuroactive compounds, and regulation via the immune mediated MGBA

This process depends on the TNF signaling pathway and involves 2-hydroxyglutarate accumulation and KDM1A-mediated demethylation, identifying potential therapeutic targets for allergic asthma (146)
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