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In addition, in studies on GLN metabolism, N6-methyladenosine (m 6 A) regulates GLN metabolism through modification of insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2), which directly or indirectly promotes AML cell development and self-renewal, and higher levels of IGF2BP2 expression correlate with a poor prognosis for AML [53]

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They performed a high throughput miRNA array analysis using a cohort of stage 1 adenocarcinomas and found that miR-486 was the most downregulated miRNA in lung tumors compared to adjacent uninvolved lung tissues

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However, there were significant and dose-dependent increases in working memory by level of SF and its metabolites measured in the urine of these subjects [215]

Steinhauser, C., Seifert, G