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Furthermore, the endoplasmic reticulum (ER) is another cellular source for ROS due to alterations in ER-regulated protein folding pathways [13]

Together, they help firm up the skin, reduce melanin, and keep that bouncy, youthful texture intact

MG has two functional groups, which can be either oxidized or reduced, due to which it acts as a substrate for various oxidoreductase and dehydrogenase enzymes 33

The data were quantified as described in Fig 5

NRF2 Nuclear factor erythroid 2-related factor 2 [56] is a fundamental local transcription element that promotes resistance to ferroptosis and is crucial for preserving the balance of antioxidants and metabolic stability in cells [56]

In: Barreiro C., Barredo J.-L., editors