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Description
Evidence from patients with HD and from rodent models implicates brain-derived neurotrophic factor (BDNF)-TrkB signalling deficiency in the pathogenesis of HD 10
Vahter ME, Mottet NK, Friberg LT, Lind SB, Charleston JS, Burbacher TM

Independent testing, easy to verify

Methods Synthesis of chemical compounds Details are collected in the Supplementary Information (Supplementary Figures 817 and Supplementary Methods) Stock solutions of Sav, 1 , 2 , ArM 2 x Sav, and ArM 2 x 5 y Sav x x y Sav-stock solutions (stock A ) were prepared in phosphate-buffered saline (PBS) (pH 7.5) or water to yield 800 M free biotin-binding site (referred to as FBBS)

Frudd, K

Autophagy maintains cellular homeostasis and energy production, to allow cells to function normally, and is a protective mechanism induced in response to multiple stressors [7, 8]
