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Given that the probable mechanism of action-altering E-I neural balance is likely to be beneficial in a range of conditions, trials should include a broad range of outcome measures in addition to SOR

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Recapitulating and reversing human brain ribosomopathy defects via the maladaptive integrated stress response

doi: 10.1007/164_2016_103 184 OrmsbeeHSFondacaroJD

Borrelli, E., Sawchenko, P.E., Evans, R.M

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