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pharmacological inhibition of NNMT has therefore become a major focus in laboratory research on adipose-tissue energy balance, methyl-donor recycling, and metabolic resilience

doi: 10.1016/j.ejpb.2018.06.011
These antidepressants inhibit the liver enzyme CYP2D6, which is crucial for metabolizing Tramadol

used an intravenously administered alcohol clamp and found that a high-carb meal, but not an equicaloric high-fat or high-protein meal, increased AER (190)
