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One of the approaches to enhance soluble expression is co-expression of protein chaperones [14]

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Radiation can lead to the deletion of the extracellular domain of normal EGFR

The follow-up that matters for this specific compound landed in 2018, when a small-molecule NNMT inhibitor was given to obese mice

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doi: 10.1016/S0141-3910(02)00003-4