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Heart 106, 691697
Norwalk, CT: Appleton & Lange
Chandimali N, et al
& Smith, C.J
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The shift from laboratory-scale to industrial-scale production frequently results in variability in vesicle size, lamellarity, encapsulation efficiency, and batch consistency, largely due to the sensitivity of liposome characteristics to process parameters like hydration rate, extrusion pressure, and lipid composition