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Metal-triggered structural transformations, aggregation, and fibrillation of human -synuclein: a possible molecular link between parkinsons disease and heavy metal exposure

Stamatakis MK, Leader WG

Finally, we investigated the mechanisms of enhanced autophagy activity in Th1, CTL, and Tem

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Cell 56 , 13941407 (2021)

During anaplerosis, mitochondrial glutamate dehydrogenase 1 (GLUD1) plays a key role by catalyzing the conversion of glutamate to alpha-ketoglutarate (-KG) and releasing ammonia, which regulates autophagy and neutralizes the intracellular pH in cancer cells 19,20