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Additionally, it was demonstrated TanIIA may activate Nrf2/GSH signalling to restrain myofibroblast proliferation by limiting glutamate availability to support cell growth ( via activation of the Nrf2 pathway in human alveolar epithelial cells and human bronchial epithelial cells (Feng et al., 2020b)

To confirm whether selenomethionine can be converted into selenocysteine through the transsulfuration pathway to regulate the protein levels of GPX4, we detected the GPX4 of OS-RC-2, HepG2, and HT1080 cultured in medium with or without selenomethionine, cystine or RSL3

Cancers 11 (5), 606

The total glutathione content was determined using high-pressure liquid chromatography (HPLC) [38]

Inhibition of LDHB upregulates STAT1, suppresses SLC7A11 expression and disrupts GSH metabolism, thereby surmounting intrinsic ferroptosis resistance in this subtype (131)