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Estrogen receptor signaling is reprogrammed during breast tumorigenesis

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Long non-coding RNAs (lncRNAs) are typically longer than 200 nucleotides and they control gene expression by remodeling chromatin, interference of transcription, and miRNA sponges (107)

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A specific protease site engineered between the GST moiety and the protein of interest allows removal of the GST moiety from the target recombinant protein