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Obesity in pregnancylong-term effects on offspring hypothalamic-pituitary-adrenal axis and associations with placental cortisol metabolism: a systematic review

[DOI] [PubMed] [Google Scholar] 207.Sun L, Pan S, Yang Y, Sun J, Liang D, Wang X

A companion phase III trial reported a -10.9% reduction in visceral adipose tissue (a 21 cm decrease) in the tesamorelin group compared with -0.6% in the placebo group over the six-month efficacy phase, alongside significant improvements in trunk fat, waist circumference, and waist-hip ratio, with the authors concluding that tesamorelin reduces visceral fat by approximately 18% and improves body-image distress in HIV-infected patients with central fat accumulation, without significant side effects or disruption of glucose control

Liao, B., Zhao, Y., Wang, D., Zhang, X., Hao, X., and Hu, M

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