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Decreased Intake issues: A vegan or vegetarian diet with no animal products Poor Absorption Issues Medications that block absorption of B12 Pernicious anemia Auto-immune disorders An Helicobacter pylori (H

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Moreover, enhanced phosphorylation of AMPK and unc-51 like autophagy activating kinase 1 (ULK1), along with reduced p-p70S6K and p-mTOR levels, were observed in PTX-resistant cells compared to PTX-sensitive cells ( Figure 5C )