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The peptides in this category signal the body to repair mitochondria, switch fuel sources, activate fat-burning pathways, and produce energy more reliably without stimulants that wear off or crash

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(92) conducted a 16-week randomized, double-blind, controlled trial with 196 patients, finding that omega-3 PUFAs significantly reduced the total number of migraine attacks compared to placebo, though a strong placebo effect was observed, and the study did not confirm earlier findings from smaller studies