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Indeed, as shown through selected examples, in Figures 2S and 3S of the Supplementary Information, although their intensity was generally found to decrease, even remarkably, with fermentation time, peaks located at the retention times of vicine and convicine were clearly detected in the XIC traces obtained for the m/z ratios 305.3 and 306.3, respectively

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2BE and Supplementary Fig

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This age-related NAD+ depletion has prompted interest in NAD+ supplementation strategies to support cellular metabolism and possibly counteract aspects of aging

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