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It acts as a signaling molecule that: Activates tissue repair pathways Stimulates collagen and glycosaminoglycan synthesis Promotes angiogenesis Modulates inflammation via NF-B suppression When endogenous levels fall, regenerative capacity falls in tandem

M., Scherrer, B., Harvey, A

doi:10.1016/j.eururo.2011.05.043

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TABLE 10 Structures of six metabolites identified by high-performance liquid chromatography-tandem mass spectrometry in rat plasma, bile, urine, and feces following a single intramuscular administration of 100 g/300 Ci/kg of [3H]BPC157