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doi: 10.1007/978-1-4939-2288-8_9 342 AkmanMMonteleoneCDoronzoGGodelMNapoliFMerliniAet al

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Nontoxic, biodegradable hyperbranched poly (-amino ester) s for efficient siRNA delivery and gene silencing

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Disease severity was categorized as 1 or 2 according to the WHO clinical ordinal scale 19

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This large difference means that there is an insurmountable concentration gradient that prohibits extracellular glutathione entering cells

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Theoretically, if homocysteine concentrations become extremely low, substrate availability for glutathione synthesis could also be reduced

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