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[DOI] [PubMed] [Google Scholar] 167.Ziats MN, Comeaux MS, Yang Y, Scaglia F, Elsea SH, Sun Q, Beaudet AL, Schaaf CP

39 , e143 (2011)

Another new insight came from knock-out of the mysterious type 2 IGF receptor, identical to the mannose-6 phosphate receptor (M6P-R), specifically binding IGF-II and involved in internalization of proteins for lysosomal degradation

Restoring mitochondrial health could increase the antigen-presenting ability of aged DCs

Given that mitochondrial dysfunction is an important factor for ferroptosis (146), Parkins role in mitophagy suggests a potential link

Jastreboff, MD, PhD Director, Weight Management & Obesity Prevention Yale School of Medicine, New Haven, Connecticut Professor Ania Jastreboff has been a principal investigator for pivotal GLP3 clinical trials, including the landmark phase 2 obesity study published in the New England Journal of Medicine