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The most advanced of the prodrug candidates is TLK286, -glutamyl- -amino- -(2-ethyl- N , N , N , N -tet-rakis (2-chloroethyl) phosphorodiamidate)-sulfonyl-propionyl-( R )-() phenylglycine)

Mitochondrial hyperpolarization and ATP depletion in patients with systemic lupus erythematosus

Sato H, Shiiya A, Kimata M, Maebara K, Tamba M, Sakakura Y, Makino N, Sugiyama F, Yagami K, Moriguchi T, et al

Maintaining iron levels within cells is a finely tuned process regulated by the orchestrated interplay of various factors during ferroptosis [103]

doi:10.1002/cmdc.200700015

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