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Many conditions may lead to nerve damage or peripheral neuropathy, physical injury vitamin deficiencies, such as a vitamin B12 deficiency diabetes autoimmune diseases kidney and liver conditions some infections, such as Lyme disease and HIV Treatment It is possible to treat carpal tunnel syndrome by relieving pressure on the nerve

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Efficacy and safety of fortification and supplementation with vitamin B12: biochemical and physiological effects

CouffinhalTKearneyMWitzenbichlerBChenDMuroharaTLosordoDWet al

A study comparing bioavailability of crystalline B12 at different oral doses found that the body can only absorb about 1-1.2 mcg B12 via the gut per dose