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Natural substances and Alzheimers disease: From preclinical studies to evidence based medicine

L-Carnitine 1200mg is a naturally occurring amino-acidderived compound studied in pre-clinical laboratory models for its role in cellular energy transport , mitochondrial signaling , and metabolic pathway coordination

Yang D, Liu H, Cai Y, Lu K, Zhong X, Xing S, et al

For evaluating individual metabolites, the number of effective tests (NEF) 90 was used to adjust for multiple comparisons as NEF has the advantage of accounting for the high correlation structure of the metabolomics data

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