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On one hand, ROS can directly modify -syn, accelerating its abnormal aggregation

Role of cytochrome c as a stimulator of -synuclein aggregation in lewy body disease

Peptides, especially complex ones, are delicate molecules

Trends and Emerging Information: As of 2024, glutathione skin treatment continues to gain popularity in India, especially L-glutathione injections in Mumbai where patients look for safe, FDA-approved solutions

Generation of NADPH via Complementary Pathways NADPH is regenerated in the cytosol via three metabolic routes: G6PD utilizes glucose to produce NADPH via the PPP, whereas malic enzyme 1 (ME1) and isocitrate dehydrogenase 1 (IDH1) use tricarboxylic acid (TCA) cycle intermediates

Karhade is a fellow of the American Academy of Dermatology and a member of the American Society for Dermatologic Surgery