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1e has also been suggested (and is still commonly propagated) for HEDS as a non-glutathione substrate 9,57

Resveratrol increases nitric oxide synthase, induces accumulation of p53 and p21(WAF1/CIP1), and suppresses cultured bovine pulmonary artery endothelial cell proliferation by perturbing progression through S and G2

Furthermore, systemic and localized inflammation was markedly increased, as evidenced by elevated levels of inflammatory cytokines in serum, cortex, and tumor tissues

doi: 10.3389/fendo.2023.1171886 161 Lagunas-RangelFAKoshelevDNedorubovAKoshelevaLTrukhanVRabinovitchAet al

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