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The trial period was 12 weeks and the dose was 60 mg/kg/day in three doses with a maximum of 4,200 mg/day

Although mitochondrial respiration was noted as unchanged in resting and stimulated CD4+ and CD8+ T cells, CD8+ T cells were found to have a reduction in proton leak, ATP synthesis, and mitochondrial membrane potential (254)

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Nugroho et al

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"Boston Men" on the Northwest Coast: The American Maritime Fur Trade 1788-1844
