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The metabolomic profiles of these elders suggested changes in the pentose phosphate, the mevalonate, the beta-oxidation, and the xanthine oxidase pathways, together with the changes in the urea cycle and the increased neurotransmitter precursors after 18 months of intervention [187]
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doi: 10.1016/S0015-0282(16)41589-X
Furthermore, the accumulation of senescence-associated -galactosidase (SA--gal) due to increased lysosomal content indicates metabolic changes associated with aging 29
It is built with stones and logs, and its main function was to serve as a strategic control point to protect the citadel from possible invaders
The practical application of antioxidant to prevent OsG/ROS stress-induced damages would be in the endogenous antioxidant form,GSH
