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From 5 million transformants the group identified two 8mer peptides, cyclic-peptide 1 and 2 (CP1 and CP2), that specifically reduced toxicity of expressed human S, and prevented dopaminergic neuron loss in a C.elegans PD model [86]

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Another member of the Wnt pathway and direct Wnt target gene frequently associated with stem cells is the negative regulator Axin2 (Figure 1