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Description
4 Actinic lentigo Clinical features Actinic lentigines (also known as lentigo senilis, solar lentigo, senile freckle, senile lentigo, liver spot) are benign, irregular, macular lesions that commonly develop on sun-damaged skin of the middle aged and elderly, and are therefore most numerous on the face and dorsal aspects of the hands and forearms (Figs 25.13, 25.14)

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Cell Rep 9:14951506

ALCAR and KET also activated brainstem nuclei (locus coeruleus, diagonal band, and raphe nuclei) which send aminergic projections to cortical areas and spinal dorsal horns that are involved in pain and mood control (Khan and Stroman, 2015)

Nature 388 , 839840 (1997)

Additionally, research indicates that ALCAR supports mitochondrial function and cellular energy production, particularly in aging tissues where mitochondrial efficiency naturally declines [4]