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Finally, the NAD + -dependent lipoamide dehydrogenase activity of FAD-containing E3 returns the lipoyl sulfurs to their oxidized, disulfide-bonded state for another round of catalysis

Quemeneur, L

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Seminars in cell & developmental biology 23 , 729737, (2012)

Plus, using precision testing to detect oxidative stress status before disease development can potentially stop age-related illness in its tracks

SnCE1 is N-terminally proteolytically processed in eukaryotic cells We expressed full length wild type SnCE1 and the non-acetylated mutants SnCE1 Y212A and SnCE1 C256A with C-terminal myc-His 6 -tag in HEK-293 cells and performed immunoblotting to analyze whether processing occurs from the N- or C-terminus (Fig