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Reduced hippocampal neurogenesis in adult transgenic mice with chronic astrocytic production of interleukin-6
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Matt Kaeberlein (UW Medicine, Optispan) observed: Expecting a single drug to meaningfully alter the course of Alzheimers once cognitive decline is underway is an extraordinarily high bar. The EVOKE population already had MCI or mild dementiameaning pathological cascades were well-established
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