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The evidence of new bone formation covered a smaller area of the bone marrow, at the expense of the formation of cortical bone in the treated animals compared to the cortex in the control animals

Western Blot Analysis Cell extracts were prepared in lysis buffer containing Tris-HCl, pH 7.5, 150 mM NaCl, 1 mM EDTA, 2 mM DTT, 2 mM PMSF and 1% Triton X-100 followed by ultrasonication method

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[DOI] [PubMed] [Google Scholar] 76.Partida-Snchez S, Cockayne DA, Monard S, Jacobson EL, Oppenheimer N, Garvy B, et al

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NNMT-mediated SAM depletion can alter cell MP, contributing to the change in global epigenetic histone profiles in cancer (7, 93)
