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glutathione and parasites Thioredoxin Reductase from Schistosoma mansoni: An Essential Parasite Enzyme a Key Drug Target Possible mechanisms of haem toxicity

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glutathione and parasites Thioredoxin Reductase from Schistosoma mansoni: An Essential Parasite Enzyme a Key Drug Target Possible mechanisms of haem toxicity

It is administered through small subcutaneous injections

glutathione and parasites Thioredoxin Reductase from Schistosoma mansoni: An Essential Parasite Enzyme a Key Drug Target Possible mechanisms of haem toxicity

Notably, pharmacological blockade of opioid and benzodiazepine receptors partially reversed AST-mediated neuroprotection, suggesting that receptor-dependent mechanisms may contribute to its cognitive benefits beyond classical antioxidant activity (Rastinpour et al., 2025)

glutathione and parasites Thioredoxin Reductase from Schistosoma mansoni: An Essential Parasite Enzyme a Key Drug Target Possible mechanisms of haem toxicity

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glutathione and parasites Thioredoxin Reductase from Schistosoma mansoni: An Essential Parasite Enzyme a Key Drug Target Possible mechanisms of haem toxicity

A further animal study from 2016 confirmed immunomodulatory effects

glutathione and parasites Thioredoxin Reductase from Schistosoma mansoni: An Essential Parasite Enzyme a Key Drug Target Possible mechanisms of haem toxicity

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glutathione and parasites Thioredoxin Reductase from Schistosoma mansoni: An Essential Parasite Enzyme a Key Drug Target Possible mechanisms of haem toxicity

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