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24 GLP-1, used for treating diabetes, is quickly broken down in the body, requiring high doses that can cause side effects like nausea

Under hypoxia, HIF-1 upregulates PDK1, reinforcing the glycolytic phenotype (238)

Cerium oxide NPs (nanoceria) Cerium oxide NPs (nanoceria) possess intrinsic antioxidant features as they have the potential to switch between Ce 3+ and Ce 4+ oxidation states, mimicking the activity of natural antioxidant enzymes

Abstract Immune nutrition, as an integral component of nutritional support therapy, has garnered significant attention and research in the treatment of gastrointestinal malignancies

Even though superoxide dismutase is an important antioxidant enzyme, several studies have found that high dosages of superoxide dismutase promote lipid peroxidation, produce OH, and cause cell death (Fig