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4 Therapeutic strategies targeting GPX4 for OA 4.1 Drugs directly Inhibiting lipid peroxidation or enhancing GPX4 activity 4.1.1 Classical ferroptosis inhibitors Ferrostatin-1(Fer-1) and Liproxstatin-1(Lip-1) are among the first identified and widely used specific small molecule inhibitors of ferroptosis

Seppen J, Steenken E, Lindhout D, Bosma PJ, Elferink RP

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Specifically, 426 and 969 genes showed significantly higher and lower expression, respectively, in the recurrence group than in the non-recurrence group, based on the criteria of FC 2 and p 0.05 (Additional Files 23)

Here is what a well-managed protocol produces in the first three months