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To view a copy of this licence, visit About this article Cite this article Ansari, W.A., Srivastava, K., Nasibullah, M

Heliyon 10:e30426

Although repurposing existing drugs offers a cost-effective and time-efficient alternative for identifying new therapies, their effective concentrationsmeasured as the half-maximal inhibitory concentration (IC50)often exceed the maximum safe plasma levels in humans, creating a major barrier to clinical application

doi: 10.1016/j.ejphar.2008.03.008 239
[DOI] [PMC free article] [PubMed] [Google Scholar] 105.Sawa T., Ono K., Tsutsuki H., Zhang T., Ida T., Nishida M., Akaike T

[PubMed 15488056] 2614
