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The copper ion serves as an essential cofactor for enzymes involved in extracellular matrix maintenance including lysyl oxidase and superoxide dismutase

This ultrashort peptide consists of just three amino acidsglutamic acid, aspartic acid, and argininewith a molecular weight of approximately 418 daltons

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Consequently, VRK2 expression emerges as a dual-function biomarker: its targeted inhibition shows therapeutic efficacy in VRK2-high malignancies, while its deficiency serves as a predictive indicator for metabolic-targeted interventions

Lebers hereditary optic neuropathy: B12 supplementation can worsen the conditionconsult a specialist (MedlinePlus)