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[DOI] [PubMed] [Google Scholar] 3.Ballios B.G., Cooke M.J., Donaldson L., Coles B.L., Morshead C.M., van der Kooy D., Shoichet M.S

Chronic aspartame intake causes changes in the trans-sulphuration pathway, glutathione depletion and liver damage in mice
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doi: 10.1289/ehp.845537

Altogether, IGF-1 signaling produces renal hypertrophy and increases glomerular filtration rate (GFR)

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