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It is documented that the activation of SIRT1 stimulates the expression of c-Myc by promoting the degradation of FOXO1 to prevent endothelial cell dysfunction and angiogenesis induced by hyperglycemia [81]

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Pitfall: large volumes can cause hyperchloremic metabolic acidosis and increased interstitial edema

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Enhanced ascorbic acid accumulation through overexpression of dehydroascorbate reductase confers tolerance to methyl viologen and salt stresses in tomato

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& Mendel, R

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doi: 10.3390/ijms21155338 37 GramegnaA.AmatiF.TerranovaL.SotgiuG.TarsiaP.MigliettaD.et al

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NOX1,4 and 5 are expressed in smooth muscle cells and NOX2 and 4 are expressed in cardiomyocytes, fibroblasts, or endothelial cells

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