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demonstrated how melatonin enhanced the HAT activity of CPB/p300 histone proteins in the MAPK/ERK1/2 signaling pathway on neuronal stem cells correcting the abnormal phosphorylation through acetylation of histone proteins at lysine 14 (H3K14) (Li et al., 2017a), thus reducing the hyperphosphorylated effects on tau

When compared to controls, AD patients have greater levels of lipid peroxides in their CSF (Mizoi et al., 2014

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Measurement of nitrogenase activity Nitrogenase activity was measured as acetylene-reducing activity (ARA) 43

Ectopic fat deposition occurs in organs other than the liver, such as the heart, pancreas, and skeletal muscle, leading to cardiometabolic complications in patients with MASLD [18]