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B12, dare we say it, has become almost fashionable

At the same time, activation of these pathways has a neuroprotective effect, helping to protect existing neurons from oxidative stress, inflammation, and other damaging factors

Blain EJ, Mason DJ, Duance VC

The GPCR arranges itself into a tertiary structure resembling a barrel, with the seven transmembrane helices forming a cavity within the plasma membrane that serves a ligand-binding domain that is often covered by EL-2

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